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The connection between the renal lesion and the heart is obvious; for where structural disease affects the kidney the elimination of urinary solids is sp greatly obstructed that their retention results in vaso-motor irritation that interrupts the passage of the blood through the capillaries, and subjects the heart to a great increase of propulsive power, and hypertrophy Cardiac degeneration is intimately associated with hypertrophy consequent upon valvular lesions or chronic mail Blight's disease, inasmuch as these processes induce degenerative changes in the aorta, which lessen the activity of the circulation, and develop the same difficulty in the coronary arteries.

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